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Detection of Early Response to Temozolomide Treatment in Brain Tumors Using Hyperpolarized (13)C MR Metabolic Imaging
PURPOSE: To demonstrate the feasibility of using DNP hyperpolarized [1-(13)C]-pyruvate to measure early response to temozolomide (TMZ) therapy using an orthotopic human glioblastoma xenograft model. MATERIALS AND METHODS: Twenty athymic rats with intracranial implantation of human glioblastoma cells...
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| Veröffentlicht in: | J Magn Reson Imaging |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4983457/ https://ncbi.nlm.nih.gov/pubmed/21590996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmri.22563 |
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