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Effect of low-expression gene filtering on detection of differentially expressed genes in RNA-seq data

We compare methods for filtering RNA-seq lowexpression genes and investigate the effect of filtering on detection of differentially expressed genes (DEGs). Although RNA-seq technology has improved the dynamic range of gene expression quantification, low-expression genes may be indistinguishable from...

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Bibliografiske detaljer
Udgivet i:Conf Proc IEEE Eng Med Biol Soc
Main Authors: Sha, Ying, Phan, John H., Wang, May D.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983442/
https://ncbi.nlm.nih.gov/pubmed/26737772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/EMBC.2015.7319872
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