Statistical methods on detecting differentially expressed genes for RNA-seq data

BACKGROUND: For RNA-seq data, the aggregated counts of the short reads from the same gene is used to approximate the gene expression level. The count data can be modelled as samples from Poisson distributions with possible different parameters. To detect differentially expressed genes under two situ...

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Autores principales: Chen, Zhongxue, Liu, Jianzhong, Ng, Hon Keung Tony, Nadarajah, Saralees, Kaufman, Howard L, Yang, Jack Y, Deng, Youping
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287564/
https://ncbi.nlm.nih.gov/pubmed/22784615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-S3-S1
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