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Relationship of Endothelin-1 and NLRP3 Inflammasome Activation in HT22 Hippocampal Cells in Diabetes

Diabetes increases the risk and worsens the progression of cognitive decline. Diabetic rats treated with the dual endothelin receptor antagonist bosentan, have been shown to improve hippocampal-based cognitive deficits. The NLRP3 inflammasome has been implicated in vascular complications of diabetes...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Life Sci
Hauptverfasser: Ward, Rebecca, Ergul, Adviye
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983268/
https://ncbi.nlm.nih.gov/pubmed/26883974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2016.02.043
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