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Bidirectional homeostatic regulation of a depression-related brain state by GABAergic deficits and ketamine treatment
BACKGROUND: Major depressive disorder (MDD) is increasingly recognized to involve functional deficits in both GABAergic and glutamatergic synaptic transmission. To elucidate the relationship between these phenotypes we made use of GABA(A) receptor γ2 subunit heterozygous (γ2(+/−)) mice, which we pre...
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| 出版年: | Biol Psychiatry |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4983262/ https://ncbi.nlm.nih.gov/pubmed/27062563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2016.02.009 |
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