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Bidirectional homeostatic regulation of a depression-related brain state by GABAergic deficits and ketamine treatment
BACKGROUND: Major depressive disorder (MDD) is increasingly recognized to involve functional deficits in both GABAergic and glutamatergic synaptic transmission. To elucidate the relationship between these phenotypes we made use of GABA(A) receptor γ2 subunit heterozygous (γ2(+/−)) mice, which we pre...
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| Veröffentlicht in: | Biol Psychiatry |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4983262/ https://ncbi.nlm.nih.gov/pubmed/27062563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2016.02.009 |
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