Bidirectional homeostatic regulation of a depression-related brain state by GABAergic deficits and ketamine treatment

BACKGROUND: Major depressive disorder (MDD) is increasingly recognized to involve functional deficits in both GABAergic and glutamatergic synaptic transmission. To elucidate the relationship between these phenotypes we made use of GABA(A) receptor γ2 subunit heterozygous (γ2(+/−)) mice, which we pre...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Biol Psychiatry
Main Authors: Ren, Zhen, Pribiag, Horia, Jefferson, Sarah J., Shorey, Matthew, Fuchs, Thomas, Stellwagen, David, Luscher, Bernhard
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983262/
https://ncbi.nlm.nih.gov/pubmed/27062563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2016.02.009
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki