Omeprazole impairs vascular redox biology and causes xanthine oxidoreductase-mediated endothelial dysfunction

Proton pump inhibitors (PPIs) are widely used drugs that may increase the cardiovascular risk by mechanisms not entirely known. While PPIs increase asymmetric dimethylarginine (ADMA) levels and inhibit nitric oxide production, it is unknown whether impaired vascular redox biology resulting of increa...

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Vydáno v:Redox Biol
Hlavní autoři: Pinheiro, Lucas C., Oliveira-Paula, Gustavo H., Portella, Rafael L., Guimarães, Danielle A., de Angelis, Celio D., Tanus-Santos, Jose E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983109/
https://ncbi.nlm.nih.gov/pubmed/27521759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.08.001
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