Overexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner

BACKGROUND: Overexpression the KCNJ3, a gene that encodes subunit 1 of G-protein activated inwardly rectifying K(+) channel (GIRK1) in the primary tumor has been found to be associated with reduced survival times and increased lymph node metastasis in breast cancer patients. METHODS: In order to sur...

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Udgivet i:BMC Cancer
Main Authors: Rezania, S., Kammerer, S., Li, C., Steinecker-Frohnwieser, B., Gorischek, A., DeVaney, T. T. J., Verheyen, S., Passegger, C. A., Tabrizi-Wizsy, N. Ghaffari, Hackl, H., Platzer, D., Zarnani, A. H., Malle, E., Jahn, S. W., Bauernhofer, T., Schreibmayer, W.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983040/
https://ncbi.nlm.nih.gov/pubmed/27519272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2664-8
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