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A trinucleotide can promote metal ion-dependent specific cleavage of RNA.

Nucleotide sequence and metal ion requirements for Mn(2+)-dependent self-cleavage of an RNA 31 nucleotides long [Dange, V., Van Atta, R. B. & Hecht, S. M. (1990) Science 248, 585-588] were examined by analysis of the site-specific cleavage activity of substitution and deletion mutants as well as com...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Kazakov, S, Altman, S
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1992
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49830/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1518817/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.17.7939
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