Congenital B-lymphoblastic leukemia with a cryptic MLL rearrangement and post-treatment evolution to mixed phenotype acute leukemia

Congenital leukemia is a rare event with a poor prognosis. We report a case of congenital leukemia with a cryptic rearrangement of MLL demonstrable only with RT-PCR. Interestingly, with treatment, the patient showed lineage plasticity of the leukemia with the development of monocytic lineage blasts...

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Publicado en:Leuk Res Rep
Main Authors: Moschiano, Elizabeth, Raca, Gordana, Fu, Cecilia, Pattengale, Paul K., Oberley, Mathew J.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982915/
https://ncbi.nlm.nih.gov/pubmed/27547725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lrr.2016.07.002
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