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Optimization of the Expression Conditions of CGA-N46 in Bacillus subtilis DB1342(p-3N46) by Response Surface Methodology

CGA-N46 is a small antifungal-derived peptide and consists of the 31st–76th amino acids of the N-terminus of human chromogranin A. Polycistronic expression of recombinant CGA-N46 in Bacillus subtilis DB1342 was used to improve its production, but the yield of CGA-N46 was still low. In the present st...

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Vydáno v:Interdiscip Sci
Hlavní autoři: Li, Rui-Fang, Wang, Bin, Liu, Shuai, Chen, Shi-Hua, Yu, Guang-Hai, Yang, Shuo-Ye, Huang, Liang, Yin, Yan-Li, Lu, Zhi-Fang
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982894/
https://ncbi.nlm.nih.gov/pubmed/26341498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12539-015-0115-x
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