Prospective validation of rapid plasma genotyping as a sensitive and specific tool for guiding lung cancer care

IMPORTANCE: Plasma genotyping of cell-free DNA (cfDNA) has the potential to allow for rapid noninvasive genotyping while avoiding the inherent shortcomings of tissue genotyping and repeat biopsies. OBJECTIVE: To prospectively validate plasma droplet digital PCR (ddPCR) for the rapid detection of com...

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Bibliographic Details
Published in:JAMA Oncol
Main Authors: Sacher, Adrian G., Paweletz, Cloud, Dahlberg, Suzanne E., Alden, Ryan S., O’Connell, Allison, Feeney, Nora, Mach, Stacy L., Jänne, Pasi A., Oxnard, Geoffrey R.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982795/
https://ncbi.nlm.nih.gov/pubmed/27055085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2016.0173
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