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A Mechanistic Model for Cooperative Behavior of Co-transcribing RNA Polymerases

In fast-transcribing prokaryotic genes, such as an rrn gene in Escherichia coli, many RNA polymerases (RNAPs) transcribe the DNA simultaneously. Active elongation of RNAPs is often interrupted by pauses, which has been observed to cause RNAP traffic jams; yet some studies indicate that elongation se...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Heberling, Tamra, Davis, Lisa, Gedeon, Jakub, Morgan, Charles, Gedeon, Tomáš
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982667/
https://ncbi.nlm.nih.gov/pubmed/27517607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005069
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