Molecular Structures of Transcribing RNA Polymerase I

RNA polymerase I (Pol I) is a 14-subunit enzyme that solely synthesizes pre-ribosomal RNA. Recently, the crystal structure of apo Pol I gave unprecedented insight into its molecular architecture. Here, we present three cryo-EM structures of elongating Pol I, two at 4.0 Å and one at 4.6 Å resolution,...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Tafur, Lucas, Sadian, Yashar, Hoffmann, Niklas A., Jakobi, Arjen J., Wetzel, Rene, Hagen, Wim J.H., Sachse, Carsten, Müller, Christoph W.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
Assuntos:
Short Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179497/
https://ncbi.nlm.nih.gov/pubmed/27867008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.11.013
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