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High-efficiency CRISPR/Cas9 multiplex gene editing using the glycine tRNA-processing system-based strategy in maize

BACKGROUND: CRISPR/Cas9 genome editing strategy has been applied to a variety of species and the tRNA-processing system has been used to compact multiple gRNAs into one synthetic gene for manipulating multiple genes in rice. RESULTS: We optimized and introduced the multiplex gene editing strategy ba...

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Detalhes bibliográficos
Publicado no:BMC Biotechnol
Main Authors: Qi, Weiwei, Zhu, Tong, Tian, Zhongrui, Li, Chaobin, Zhang, Wei, Song, Rentao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982333/
https://ncbi.nlm.nih.gov/pubmed/27515683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-016-0289-2
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