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Boosting CRISPR/Cas9 multiplex editing capability with the endogenous tRNA-processing system
The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 9 nuclease (Cas9) system is being harnessed as a powerful tool for genome engineering in basic research, molecular therapy, and crop improvement. This system uses a small guide RNA (gRNA) to direct Cas9 e...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4371917/ https://ncbi.nlm.nih.gov/pubmed/25733849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420294112 |
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