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Mitochondrial metabolic remodeling in response to genetic and environmental perturbations

Mitochondria are metabolic hubs within mammalian cells and demonstrate significant metabolic plasticity. In oxygenated environments with ample carbohydrate, amino acid, and lipid sources, they are able to use the tricarboxylic acid cycle for the production of anabolic metabolites and ATP. However, i...

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Bibliographic Details
Published in:Wiley Interdiscip Rev Syst Biol Med
Main Authors: Hollinshead, Kate E.R., Tennant, Daniel A.
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Inc. 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982039/
https://ncbi.nlm.nih.gov/pubmed/27196610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wsbm.1334
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