Multisite tyrosine phosphorylation of the N‐terminus of Mint1/X11α by Src kinase regulates the trafficking of amyloid precursor protein

Mint/X11 is one of the four neuronal trafficking adaptors that interact with amyloid precursor protein (APP) and are linked with its cleavage to generate β‐amyloid peptide, a key player in the pathology of Alzheimer's disease. How APP switches between adaptors at different stages of the secreto...

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Vydáno v:J Neurochem
Hlavní autoři: Dunning, Christopher J. R., Black, Hannah L., Andrews, Katie L., Davenport, Elizabeth C., Conboy, Michael, Chawla, Sangeeta, Dowle, Adam A., Ashford, David, Thomas, Jerry R., Evans, Gareth J. O.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
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ORIGINAL ARTICLES
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982022/
https://ncbi.nlm.nih.gov/pubmed/26865271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13571
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