Human umbilical cord-derived mesenchymal stem cells protect against experimental colitis via CD5(+) B regulatory cells

BACKGROUND: To clarify the effect of human umbilical cord-derived mesenchymal stem cell (hUC-MSCs) treatment on colitis and to explore the role of CD5(+) B cells in MSC therapy. METHODS: The trinitrobenzenesulfonic acid (TNBS)-induced colitis mouse model was used. HUC-MSCs were transferred peritonea...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Chao, Kang, Zhang, Shenghong, Qiu, Yun, Chen, Xiaoyong, Zhang, Xiaoran, Cai, Chuang, Peng, Yanwen, Mao, Ren, Pevsner-Fischer, Meirav, Ben-horin, Shomron, Elinav, Eran, Zeng, Zhirong, Chen, Baili, He, Yao, Xiang, Andy Peng, Chen, Minhu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981968/
https://ncbi.nlm.nih.gov/pubmed/27515534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-016-0376-2
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