The Cerebrospinal Fluid Neurogranin/BACE1 Ratio is a Potential Correlate of Cognitive Decline in Alzheimer’s Disease

Background: In diagnosing Alzheimer’s disease (AD), ratios of cerebrospinal fluid (CSF) biomarkers, such as CSF Aβ(1-42)/tau, have an improved diagnostic performance compared to the single analytes, yet, still a limited value to predict cognitive decline. Since synaptic dysfunction/loss is closely l...

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Bibliografiske detaljer
Udgivet i:J Alzheimers Dis
Main Authors: De Vos, Ann, Struyfs, Hanne, Jacobs, Dirk, Fransen, Erik, Klewansky, Tom, De Roeck, Ellen, Robberecht, Caroline, Van Broeckhoven, Christine, Duyckaerts, Charles, Engelborghs, Sebastiaan, Vanmechelen, Eugeen
Format: Artigo
Sprog:Inglês
Udgivet: IOS Press 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981899/
https://ncbi.nlm.nih.gov/pubmed/27392859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-160227
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