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Neuroprotective effects of apigenin against inflammation, neuronal excitability and apoptosis in an induced pluripotent stem cell model of Alzheimer’s disease

Alzheimer’s disease (AD) is one of the most prevalent neurodegenerative diseases, yet current therapeutic treatments are inadequate due to a complex disease pathogenesis. The plant polyphenol apigenin has been shown to have anti-inflammatory and neuroprotective properties in a number of cell and ani...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Balez, Rachelle, Steiner, Nicole, Engel, Martin, Muñoz, Sonia Sanz, Lum, Jeremy Stephen, Wu, Yizhen, Wang, Dadong, Vallotton, Pascal, Sachdev, Perminder, O’Connor, Michael, Sidhu, Kuldip, Münch, Gerald, Ooi, Lezanne
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981845/
https://ncbi.nlm.nih.gov/pubmed/27514990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31450
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