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Neuroprotective effects of apigenin against inflammation, neuronal excitability and apoptosis in an induced pluripotent stem cell model of Alzheimer’s disease

Alzheimer’s disease (AD) is one of the most prevalent neurodegenerative diseases, yet current therapeutic treatments are inadequate due to a complex disease pathogenesis. The plant polyphenol apigenin has been shown to have anti-inflammatory and neuroprotective properties in a number of cell and ani...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Balez, Rachelle, Steiner, Nicole, Engel, Martin, Muñoz, Sonia Sanz, Lum, Jeremy Stephen, Wu, Yizhen, Wang, Dadong, Vallotton, Pascal, Sachdev, Perminder, O’Connor, Michael, Sidhu, Kuldip, Münch, Gerald, Ooi, Lezanne
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981845/
https://ncbi.nlm.nih.gov/pubmed/27514990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31450
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