Heteroresistance to Fluconazole Is a Continuously Distributed Phenotype among Candida glabrata Clinical Strains Associated with In Vivo Persistence

Candida glabrata causes persistent infections in patients treated with fluconazole and often acquires resistance following exposure to the drug. Here we found that clinical strains of C. glabrata exhibit cell-to-cell variation in drug response (heteroresistance). We used population analysis profilin...

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Publicado en:mBio
Autores principales: Ben-Ami, Ronen, Zimmerman, Offer, Finn, Talya, Amit, Sharon, Novikov, Anna, Wertheimer, Noa, Lurie-Weinberger, Mor, Berman, Judith
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981708/
https://ncbi.nlm.nih.gov/pubmed/27486188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00655-16
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