Heteroresistance to Fluconazole Is a Continuously Distributed Phenotype among Candida glabrata Clinical Strains Associated with In Vivo Persistence

Candida glabrata causes persistent infections in patients treated with fluconazole and often acquires resistance following exposure to the drug. Here we found that clinical strains of C. glabrata exhibit cell-to-cell variation in drug response (heteroresistance). We used population analysis profilin...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Ben-Ami, Ronen, Zimmerman, Offer, Finn, Talya, Amit, Sharon, Novikov, Anna, Wertheimer, Noa, Lurie-Weinberger, Mor, Berman, Judith
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981708/
https://ncbi.nlm.nih.gov/pubmed/27486188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00655-16
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