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Distinct metabolic states can support self-renewal and lipogenesis in human pluripotent stem cells under different culture conditions
Recent studies have suggested that human pluripotent stem cells (hPSCs) depend primarily on glycolysis and only increase oxidative metabolism during differentiation. Here we demonstrate that both glycolytic and oxidative metabolism can support hPSC growth, and the metabolic phenotype of hPSCs is lar...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4981511/ https://ncbi.nlm.nih.gov/pubmed/27477285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.06.102 |
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