Preventing Spontaneous Genetic Rearrangements in the Transgene Cassettes of Adenovirus Vectors

First-generation, E1/E3-deleted adenoviral vectors with diverse transgenes are produced routinely in laboratories worldwide for development of novel prophylactics and therapies for a variety of applications, including candidate vaccines against important infectious diseases, such as HIV/AIDS, tuberc...

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Pubblicato in:Biotechnol Bioeng
Autori principali: Cottingham, Matthew G., Carroll, Fionnadh, Morris, Susan J., Turner, Alison V., Vaughan, Aisling M., Kapulu, Melissa C., Colloca, Stefano, Siani, Loredana, Gilbert, Sarah C., Hill, Adrian V.S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981243/
https://ncbi.nlm.nih.gov/pubmed/22252512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.24342
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