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Melting Point Distribution Analysis of Globally Approved and Discontinued Drugs: A Research for Improving the Chance of Success of Drug Design and Discovery

The melting point (MP), an easily accessible physical parameter, has considerable potential for the judgment of drug‐like properties. However, to the best of our knowledge, there are no useful guidelines for understanding the relationship between the MP and drug‐like properties. To this end, we have...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:ChemistryOpen
Main Authors: Mao, Fei, Kong, Qingya, Ni, Wei, Xu, Xiang, Ling, Dazheng, Lu, Zhengyu, Li, Jian
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley and Sons Inc. 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981057/
https://ncbi.nlm.nih.gov/pubmed/27547646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201600015
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