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Etoposide damages female germ cells in the developing ovary

BACKGROUND: As with many anti-cancer drugs, the topoisomerase II inhibitor etoposide is considered safe for administration to women in the second and third trimesters of pregnancy, but assessment of effects on the developing fetus have been limited. The purpose of this research was to examine the ef...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Stefansdottir, Agnes, Johnston, Zoe C., Powles-Glover, Nicola, Anderson, Richard A., Adams, Ian R., Spears, Norah
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980800/
https://ncbi.nlm.nih.gov/pubmed/27510889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2505-9
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