Natural product derivative BIO promotes recovery after myocardial infarction via unique modulation of the cardiac microenvironment

The cardiac microenvironment includes cardiomyocytes, fibroblasts and macrophages, which regulate remodeling after myocardial infarction (MI). Targeting this microenvironment is a novel therapeutic approach for MI. We found that the natural compound derivative, BIO ((2′Z,3′E)-6-Bromoindirubin-3′-oxi...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Kim, Yong Sook, Jeong, Hye-yun, Kim, Ah Ra, Kim, Woong-Hee, Cho, Haaglim, Um, JungIn, Seo, Youngha, Kang, Wan Seok, Jin, Suk-Won, Kim, Min Chul, Kim, Yong-Chul, Jung, Da-Woon, Williams, Darren R., Ahn, Youngkeun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980696/
https://ncbi.nlm.nih.gov/pubmed/27510556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30726
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