Efficient liver repopulation of transplanted hepatocyte prevents cirrhosis in a rat model of hereditary tyrosinemia type I

Hereditary tyrosinemia type I (HT1) is caused by a deficiency in the enzyme fumarylacetoacetate hydrolase (Fah). Fah-deficient mice and pigs are phenotypically analogous to human HT1, but do not recapitulate all the chronic features of the human disorder, especially liver fibrosis and cirrhosis. Rat...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Zhang, Ludi, Shao, Yanjiao, Li, Lu, Tian, Feng, Cen, Jin, Chen, Xiaotao, Hu, Dan, Zhou, Yan, Xie, Weifen, Zheng, Yunwen, Ji, Yuan, Liu, Mingyao, Li, Dali, Hui, Lijian
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980609/
https://ncbi.nlm.nih.gov/pubmed/27510266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31460
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky