Long-term in vitro maintenance of clonal abundance and leukaemia-initiating potential in acute lymphoblastic leukaemia

Lack of suitable in vitro culture conditions for primary acute lymphoblastic leukaemia (ALL) cells severely impairs their experimental accessibility and the testing of new drugs on cell material reflecting clonal heterogeneity in patients. We show that Nestin-positive human mesenchymal stem cells (M...

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Bibliografske podrobnosti
izdano v:Leukemia
Main Authors: Pal, D, Blair, H J, Elder, A, Dormon, K, Rennie, K J, Coleman, D J L, Weiland, J, Rankin, K S, Filby, A, Heidenreich, O, Vormoor, J
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980562/
https://ncbi.nlm.nih.gov/pubmed/27109511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.79
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