Long-term in vitro maintenance of clonal abundance and leukaemia-initiating potential in acute lymphoblastic leukaemia

Lack of suitable in vitro culture conditions for primary acute lymphoblastic leukaemia (ALL) cells severely impairs their experimental accessibility and the testing of new drugs on cell material reflecting clonal heterogeneity in patients. We show that Nestin-positive human mesenchymal stem cells (M...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Pal, D, Blair, H J, Elder, A, Dormon, K, Rennie, K J, Coleman, D J L, Weiland, J, Rankin, K S, Filby, A, Heidenreich, O, Vormoor, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980562/
https://ncbi.nlm.nih.gov/pubmed/27109511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.79
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