Dectin-1-activated dendritic cells trigger potent antitumour immunity through the induction of Th9 cells

Dectin-1 signalling in dendritic cells (DCs) has an important role in triggering protective antifungal Th17 responses. However, whether dectin-1 directs DCs to prime antitumour Th9 cells remains unclear. Here, we show that DCs activated by dectin-1 agonists potently promote naive CD4(+) T cells to d...

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Vydáno v:Nat Commun
Hlavní autoři: Zhao, Yinghua, Chu, Xiao, Chen, Jintong, Wang, Ying, Gao, Sujun, Jiang, Yuxue, Zhu, Xiaoqing, Tan, Guangyun, Zhao, Wenjie, Yi, Huanfa, Xu, Honglin, Ma, Xingzhe, Lu, Yong, Yi, Qing, Wang, Siqing
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980454/
https://ncbi.nlm.nih.gov/pubmed/27492902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12368
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