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γH2AX and p53 Responses in TK6 Cells Discriminate Promutagens and Non-genotoxicants in the Presence of Rat Liver S9
Previous work with a diverse set of reference chemicals suggests that an in vitro multiplexed flow cytometry-based assay (MultiFlow™ DNA Damage Kit—p53, γH2AX, Phospho-Histone H3) can distinguish direct-acting clastogens and aneugens from non-genotoxicants [Environ Mol Mutagen 57(2016)171-189]. The...
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| izdano v: | Environ Mol Mutagen |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4980245/ https://ncbi.nlm.nih.gov/pubmed/27364561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22028 |
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