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T-type calcium channel regulation of neural tube closure and EphrinA/EPHA expression
A major class of human birth defects arise from aberrations during neural tube closure (NTC). We report on a NTC signaling pathway requiring T-type calcium channels (TTCC) that is conserved between primitive chordates (Ciona) and Xenopus. With loss of TTCCs there is a failure to seal the anterior ne...
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| Udgivet i: | Cell Rep |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4980084/ https://ncbi.nlm.nih.gov/pubmed/26489462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.09.035 |
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