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miR-6734 Up-Regulates p21 Gene Expression and Induces Cell Cycle Arrest and Apoptosis in Colon Cancer Cells

Recently, microRNAs have been implicated in the regulation of gene expression in terms of both gene silencing and gene activation. Here, we investigated the effects of miR-6734, which has a sequence homology with a specific region of p21(WAF1/CIP1) (p21) promoter, on cancer cell growth and the mecha...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kang, Moo Rim, Park, Ki Hwan, Yang, Jeong-Ook, Lee, Chang Woo, Oh, Soo Jin, Yun, Jieun, Lee, Myeong Youl, Han, Sang-Bae, Kang, Jong Soon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979902/
https://ncbi.nlm.nih.gov/pubmed/27509128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160961
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