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AMPK maintains energy homeostasis and survival in cancer cells via regulating p38/PGC-1α-mediated mitochondrial biogenesis

Cancer cells exhibit unique metabolic response and adaptation to the fluctuating microenvironment, yet molecular and biochemical events imprinting this phenomenon are unclear. Here, we show that metabolic homeostasis and adaptation to metabolic stress in cancer cells are primarily achieved by an int...

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Bibliografiske detaljer
Udgivet i:Cell Death Discov
Main Authors: Chaube, B, Malvi, P, Singh, S V, Mohammad, N, Viollet, B, Bhat, M K
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979508/
https://ncbi.nlm.nih.gov/pubmed/27551487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2015.63
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