AMPK maintains energy homeostasis and survival in cancer cells via regulating p38/PGC-1α-mediated mitochondrial biogenesis

Cancer cells exhibit unique metabolic response and adaptation to the fluctuating microenvironment, yet molecular and biochemical events imprinting this phenomenon are unclear. Here, we show that metabolic homeostasis and adaptation to metabolic stress in cancer cells are primarily achieved by an int...

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Publicat a:Cell Death Discov
Autors principals: Chaube, B, Malvi, P, Singh, S V, Mohammad, N, Viollet, B, Bhat, M K
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979508/
https://ncbi.nlm.nih.gov/pubmed/27551487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2015.63
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