αTAT1 downregulation induces mitotic catastrophe in HeLa and A549 cells

α-Tubulin acetyltransferase 1 (αTAT1) controls reversible acetylation on Lys40 of α-tubulin and modulates multiple cellular functions. αTAT1 depletion induced morphological defects of touch receptor neurons in Caenorhabditis elegans and impaired cell adhesion and contact inhibition in mouse embryoni...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Discov
Prif Awduron: Chien, J-Y, Tsen, S-D, Chien, C-C, Liu, H-W, Tung, C-Y, Lin, C-H
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979442/
https://ncbi.nlm.nih.gov/pubmed/27551500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2016.6
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