αTAT1 downregulation induces mitotic catastrophe in HeLa and A549 cells

α-Tubulin acetyltransferase 1 (αTAT1) controls reversible acetylation on Lys40 of α-tubulin and modulates multiple cellular functions. αTAT1 depletion induced morphological defects of touch receptor neurons in Caenorhabditis elegans and impaired cell adhesion and contact inhibition in mouse embryoni...

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Udgivet i:Cell Death Discov
Main Authors: Chien, J-Y, Tsen, S-D, Chien, C-C, Liu, H-W, Tung, C-Y, Lin, C-H
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979442/
https://ncbi.nlm.nih.gov/pubmed/27551500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2016.6
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