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The H1047R point mutation in p110 alpha changes the morphology of human colon HCT116 cancer cells
The class IA phosphatidylinositol 3-kinases (PI3K) is involved in controlling changes in cell morphology, which is a highly coordinated cellular event. This event is powered by actin filament polymerization and remodeling. The gain-of-function mutations in the catalytic subunit of p110α of class IA...
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| Pubblicato in: | Cell Death Discov |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4979441/ https://ncbi.nlm.nih.gov/pubmed/27551473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2015.44 |
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