Novel β-carbolines against colorectal cancer cell growth via inhibition of Wnt/β-catenin signaling

Wnt signaling pathway is aberrantly activated in a variety of cancers, especially in colorectal cancer (CRC), because of mutations in the genes encoding adenomatous polyposis coli (APC), β-catenin and Axin. Small-molecule antagonists of Wnt/β-catenin signaling are attractive candidates for developin...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Death Discov
Asıl Yazarlar: Li, X, Bai, B, Liu, L, Ma, P, Kong, L, Yan, J, Zhang, J, Ye, Z, Zhou, H, Mao, B, Zhu, H, Li, Y
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979417/
https://ncbi.nlm.nih.gov/pubmed/27551464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2015.33
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