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Novel β-carbolines against colorectal cancer cell growth via inhibition of Wnt/β-catenin signaling
Wnt signaling pathway is aberrantly activated in a variety of cancers, especially in colorectal cancer (CRC), because of mutations in the genes encoding adenomatous polyposis coli (APC), β-catenin and Axin. Small-molecule antagonists of Wnt/β-catenin signaling are attractive candidates for developin...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cell Death Discov |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4979417/ https://ncbi.nlm.nih.gov/pubmed/27551464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2015.33 |
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