A Novel Agent Enhances the Chemotherapeutic Efficacy of Doxorubicin in MCF-7 Breast Cancer Cells

We have previously demonstrated that DT-010, a novel conjugate of danshensu (DSS) and tetramethylpyrazine (TMP), displays anti-tumor effects in breast cancer cells both in vitro and in vivo. In the present study, we investigated whether DT-010 enhances the chemotherapeutic effect of doxorubicin (Dox...

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Veröffentlicht in:Front Pharmacol
Hauptverfasser: Wang, Liang, Chan, Judy Y., Zhou, Xinhua, Cui, Guozhen, Yan, Zhixiang, Wang, Li, Yan, Ru, Di, Lijun, Wang, Yuqiang, Hoi, Maggie P., Shan, Luchen, Lee, Simon M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979254/
https://ncbi.nlm.nih.gov/pubmed/27559313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00249
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