Bias Correction Methods Explain Much of the Variation Seen in Breast Cancer Risks of BRCA1/2 Mutation Carriers

PURPOSE: Recommendations for treating patients who carry a BRCA1/2 gene are mainly based on cumulative lifetime risks (CLTRs) of breast cancer determined from retrospective cohorts. These risks vary widely (27% to 88%), and it is important to understand why. We analyzed the effects of methods of ris...

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Bibliografske podrobnosti
izdano v:J Clin Oncol
Main Authors: Vos, Janet R., Hsu, Li, Brohet, Richard M., Mourits, Marian J.E., de Vries, Jakob, Malone, Kathleen E., Oosterwijk, Jan C., de Bock, Geertruida H.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Clinical Oncology 2015
Teme:
Review Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979233/
https://ncbi.nlm.nih.gov/pubmed/26150446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.59.0463
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