Skin test to assess virus-specific cytotoxic T-cell activity.

A way to assess specific CD8+ T-cell activity in a skin test analogous to the conventional delayed-type hypersensitivity (DTH) reaction for CD4+ T cells is presented. Local injection of viral class I binding peptides caused a specific CD8+ T-cell-mediated DTH in footpads of virally infected mice. Th...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Kündig, T M, Althage, A, Hengartner, H, Zinkernagel, R M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49790/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1323850/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.16.7757
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