Skin test to assess virus-specific cytotoxic T-cell activity.

A way to assess specific CD8+ T-cell activity in a skin test analogous to the conventional delayed-type hypersensitivity (DTH) reaction for CD4+ T cells is presented. Local injection of viral class I binding peptides caused a specific CD8+ T-cell-mediated DTH in footpads of virally infected mice. Th...

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Bibliographic Details
Main Authors: Kündig, T M, Althage, A, Hengartner, H, Zinkernagel, R M
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC49790/
https://ncbi.nlm.nih.gov/pubmed/1323850
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