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Predictive Model of Lymphocyte-Specific Protein Tyrosine Kinase (LCK) Autoregulation

Lymphocyte-specific protein tyrosine kinase (LCK) is a key activator of T cells; however, little is known about the specific autoregulatory mechanisms that control its activity. We have constructed a model of LCK autophosphorylation and phosphorylation by the regulating kinase CSK. The model was fit...

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Publicat a:Cell Mol Bioeng
Autors principals: Rohrs, Jennifer A., Wang, Pin, Finley, Stacey D.
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978775/
https://ncbi.nlm.nih.gov/pubmed/27547268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-016-0438-7
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