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Neoplastic transformation induced by an activated lymphocyte-specific protein tyrosine kinase (pp56lck).
The lck proto-oncogene encodes a lymphocyte-specific member of the src family of protein tyrosine kinases. Here we demonstrate that pp56lck is phosphorylated in vivo at a carboxy-terminal tyrosine residue (Tyr-505) analogous to Tyr-527 of pp60c-src. Substitution of phenylalanine for tyrosine at this...
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| Publicat a: | Mol Cell Biol |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1988
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363178/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3352600/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.2.540 |
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