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An ENU-induced splicing mutation reveals a role for Unc93b1 in early immune cell activation following Influenza A H1N1 infection

Genetic and immunological analysis of host-pathogen interactions can reveal fundamental mechanisms of susceptibility and resistance to infection. Modeling human infectious diseases among inbred mouse strains is a proven approach but is limited by naturally occurring genetic diversity. Using ENU muta...

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Detalhes bibliográficos
Publicado no:Genes Immun
Main Authors: Lafferty, Erin I, Flaczyk, Adam, Angers, Isabelle, Homer, Robert, d’Hennezel, Eva, Malo, Danielle, Piccirillo, Ciriaco A, Vidal, Silvia M, Qureshi, Salman T
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978536/
https://ncbi.nlm.nih.gov/pubmed/24848930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2014.22
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