Transcriptional Profiling of Cultured, Embryonic Epicardial Cells Identifies Novel Genes and Signaling Pathways Regulated by TGFβR3 In Vitro

The epicardium plays an important role in coronary vessel formation and Tgfbr3(-/-) mice exhibit failed coronary vessel development associated with decreased epicardial cell invasion. Immortalized Tgfbr3(-/-) epicardial cells display the same defects. Tgfbr3(+/+) and Tgfbr3(-/-) cells incubated for...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: DeLaughter, Daniel M., Clark, Cynthia R., Christodoulou, Danos C., Seidman, Christine E., Baldwin, H. Scott, Seidman, J. G., Barnett, Joey V.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978490/
https://ncbi.nlm.nih.gov/pubmed/27505173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159710
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